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6-Chloro-3-methyluracil (CAS 4318-56-3)

6-Chloro-3-methyluracil

Synonyms   6-Chloro-3-methyluracil

                     6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione

                     3-Methyl-6-chlorouracil

 

Documents: COA  | MSDS

Packing  20'FCL Without /With pallets 40'FCL Without/With Pallets

1KG/Bag

25kg/Drums

N/A N/A
  • Specification
  • Feature&Application
  • Plant Details
  • FAQ
  • Properties
  • Standard

    Enterprise standard

    Appearance

    white to light yellow  powder

    Assay

    ≥99.0%

    loss on drying

    ≤1.0%

    Max single impurity

    ≤0.5%

    Residue on ignition

    ≤1.0%

  • Uses       6-Chloro-3-methyluracil  is intermediate of Alogliptin & Trelagliptin

    Alogliptin tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see Clinical Studies (14)].Important Limitations of UseAlogliptin tablets are not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis, as it would not be effective in these settings.

    Trelagliptin (Zafatek(®)) is an orally active dipeptidyl peptidase (DPP)-4 inhibitor developed by Takeda and approved in Japan for the treatment of type 2 diabetes mellitus (T2DM). Unlike other approved agents of its class, which are usually administered once daily, trelagliptin can be administered once weekly.


  • 1.  what is its main application?

    It is  intermediate of Alogliptin & Trelagliptin

    2.  how many years we produced it, and what is its capactity

    It produced since 2018。 And capacity is 50mt annually.

     

    3. what is plant location and nearest port

    It located in a chemical zone Fujian province., and nearest port is Xiamen port

    4.  if doc. Support and audit available?

    Yes, VQ and allied tech. package is available for serious client.  Audit could be accepted for clients having business more than 1 year.

    5.  what other products are producing or plan to produce in this plant 

    Advanced pharmaceutical intermediates,e.g. intermediats of Pramipexole,Rivastigmine,Ramatroban,ivacaftor,Olaparib etc.

  • Chemical Safety

     

    Irritant

     

    Property NameProperty ValueReference
    Molecular Weight 160.56 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    XLogP3-AA 0 Computed by XLogP3 3.0 (PubChem release 2019.06.18)
    Hydrogen Bond Donor Count 1 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Hydrogen Bond Acceptor Count 2 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Rotatable Bond Count 0 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Exact Mass 160.003955 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    Monoisotopic Mass 160.003955 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    Topological Polar Surface Area 49.4 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Heavy Atom Count 10 Computed by PubChem
    Formal Charge 0 Computed by PubChem
    Complexity 224 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Isotope Atom Count 0 Computed by PubChem
    Defined Atom Stereocenter Count 0 Computed by PubChem
    Undefined Atom Stereocenter Count 0 Computed by PubChem
    Defined Bond Stereocenter Count 0 Computed by PubChem
    Undefined Bond Stereocenter Count 0 Computed by PubChem
    Covalently-Bonded Unit Count 1 Computed by PubChem
    Compound Is Canonicalized Yes Computed by PubChem (release 2019.01.04)

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